Jason over @ 37 Signals has an interesting thought today.

Throw everything on your desk in a box. E V E R Y T H I N G! Only remove things as you need. Wait...and get rid of all the other crap.

I can say from experience (I'm in the process of moving, and have recently switched jobs, so I've had something like 3 diff. office spaces in 2 mos...) that when you do this, you'll be amazed, (unless you're a GTD guru like Marc) at how much shit just isn't required for you to be productive. It's just such a cleansing feeling.

Try it.